Localized immunotherapy new possibility to treat bladder cancer

Antibody-based immunotherapy is a new promising method to treat cancer. Unfortunately, today’s treatments can result in adverse side effects. New findings show an alternative way to administer the therapy, which has the same effect on the tumor but less impact other parts of the body.

Source:Localized immunotherapy new possibility to treat bladder cancer

MAO is a possible Alzheimer’s disease biomarker

Alzheimer’s disease affects more than 35 million people, a number that is expected to increase in the coming years. Currently, Alzheimer’s diagnoses rely on clinical neuropathologic assessment of amyloid-beta peptide aggregates (plaques) and neurofibrillary tangles. But now researchers reveal that an enzyme already implicated in a host of neural disorders could someday serve as a biomarker.

Source:MAO is a possible Alzheimer's disease biomarker

Scientists uncover potential driver of age- and Alzheimer’s-related memory loss

Scientists have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer’s. They found that reduced levels of a protein called Rheb result in spontaneous symptoms of memory loss in animal models and are linked to increased levels of another protein known to be elevated in the brains of Alzheimer’s disease patients.

Source:Scientists uncover potential driver of age- and Alzheimer's-related memory loss

Comparing gait parameters can predict decline in memory, thinking

Walking is a milestone in development for toddlers, but it’s actually only one part of the complex cognitive task known as gait that includes everything from a person’s stride length to the accompanying swing of each arm. A new study has found that problems associated with gait can predict a significant decline in memory and thinking.

Source:Comparing gait parameters can predict decline in memory, thinking

Benzodiazepine, related drug use increases hip fractures in persons with Alzheimer’s disease

The use of benzodiazepines and related drugs increases the risk of hip fracture by 43% in persons with Alzheimer’s disease, according to a new study. The hip fracture risk was investigated in community-dwelling Finnish persons with Alzheimer’s disease.

Source:Benzodiazepine, related drug use increases hip fractures in persons with Alzheimer's disease

Caring for the elderly, aging parents and elderly care