Tag Archives: Alzheimers

Identifying typical patterns in the progression towards Alzheimer’s disease

How the brain progresses from mild cognitive impairment (MCI) to Alzheimer’s-type dementia has been an enigma for the scientific community. However, a recent study has shed light on this progression by showing the typical patterns of the brain’s progression to dementia.

Source:Identifying typical patterns in the progression towards Alzheimer’s disease

Discovery about brain protein causes rethink on development of Alzheimer’s disease

A protein involved in the progression of Alzheimer’s disease also has properties that could be helpful for human health, a research study has found. The discovery helps researchers better understand the complicated brain chemistry behind the development of Alzheimer’s disease.

Source:Discovery about brain protein causes rethink on development of Alzheimer’s disease

Review: risk of cerebrovascular adverse events and death in elderly patients with dementia when treated with antipsychotic medications: a literature review of evidence.

Am J Alzheimers Dis Other Demen. 2011 Feb; 26(1): 10-28
Mittal V, Kurup L, Williamson D, Muralee S, Tampi RR

Behavioral and Psychological Symptoms of Dementia (BPSD) are increasingly recognized as a major risk factor for caregiver burden, institutionalization, greater impairment in activities of daily living (ADLs), more rapid cognitive decline, and a poorer quality of life. BPSD contribute significantly to the direct and indirect costs of caring for patients with dementia even after adjusting for the severity of cognitive impairment and other co-morbidities. Research on these symptoms has indicated a complex interplay between the biological, psychological and social factors involved in the disease process. Although some psychotropic medications have shown modest efficacy in the treatment of these behaviors, their use has generated controversy due to increasing recognition of the side effects of these medications especially the antipsychotic medications. In this review, we examine the risk of cerebrovascular adverse events (CVAEs) and death with antipsychotic medications when used to treat elderly patients with dementia.